加味溫膽湯의 抗高脂血作用에 대한 硏究
Study on antihyperlipidemic effect of Kamiondamtang
초록/요약
Kamiondamtang(KODT) has been used in oriental medicine as stress by many medical practitioner. For the study of KODT, we had fed mice divided to three groups(basal diet, hyperlipidemic diet, hyperlipidemic diet + KODT), and observed the change of weight, total cholesterol, triglyceride, glucose, SGOT, SGPT, HDL-cholesterol, LDL-cholesterol on the serum per every 7days for 6weeks. To help comparison with the results above, we had tested endothelial cells and liver. The results of this Study were obtained as fallows ; 1. Total cholesterol, triglyceride and LDL-cholesterol were decreased significantly by KODT. 2.. HDL-cholesterol was increasd significantly by KODT. 3. Glucose was decreased significantly by KODT. 4. SGOT was intended to decrease by KODT. 5. SGPT was decreased significantly by KODT. 6. In case of supplying KODT, WBC attatched on endothelial cells and vacuoles in muscular layer were not observed. 7. In case of supplying KODT, fatty degeneration was not observed in liver portal area.
more목차
目次 = i
ABSTRACT = ii
Ⅰ. 緖論 = 1
Ⅱ. 實驗 = 3
1. 재료 = 3
2. 방법 = 5
Ⅲ. 實驗結果 = 12
1. 고지혈증 유발에 따른 체중변화 = 12
2. 고지혈증 유발에 따른 체중변화율 = 13
3. 고지혈증 유발에 따른 cholesterol의 변화에 미치는 영향 = 14
4. 고지혈증 유발에 따른 T.Chol.의 변화에 미치는 영향 = 15
5. 고지혈증 유발에 따른 glucose의 변화에 미치는 영향 = 17
6. 고지혈증 유발에 따른 T.G.의 변화에 미치는 영향 = 19
7. 고지혈증 유발에 따른 SGOT의 변화에 미치는 영향 = 21
8. 고지혈증 유발에 따른 SGPT의 변화에 미치는 영향 = 23
9. 고지혈증 유발에 따른 HDL-Chol.의 변화에 미치는 영향 = 25
10. 고지혈증 유발에 따른 LDL-Chol.의 변화에 미치는 영향 = 27
11. 조직학적 관찰 소견 = 29
Ⅳ. 考察 = 37
Ⅴ. 結論 = 41
참고문헌 = 43