2K1C 高血壓 白鼠의 모델에 대한 心實, 腎實證 五行 瀉法 刺鍼이 血壓및 血漿 Renin, ANP에 미치는 影響
(The) Effects of reduction of five evolutive phase acupuncture techniques for appling excess in the heart, kidney on blood pressure, cardiac hypertrophy, plasma renin and ANP in hypertensive rat induced by two kidney one clip
초록/요약
Objectives : Acupuncture has been used as treatment of disease in the korean medicine. In this study, it was investigated that effcts of acupuncture at SP3·HT7, LR1·KI1 acupoints on cardiovascular system as blood pressure and renin and atrial natriuretic peptide(ANP) in plasma, cardiac hypertrophy. Materials and methods : The experiments were performed on Sprague Dawley rats, 2K1C hypertension model was prepared by constricting the left renal artery with a sliver clip. Animals were then divided into seven groups, 2K1C induced and no treated group (Control), acupuncture on SP3·HT7(AC-1), LR1·KI1 (AC-2), SP3·HT7·LR1·KI1(AC-3). The treatments were performed once a day for 10 days in rats. Results : The results are that the blood pressure was significantly decreased at 15days in AC-1 group. The cardiac hypertrophy was significantly decrease in AC-3 group. The activity of plasma ANP was increased in all groups without AC-1 group and the that of plasma Rein was decrease in AC-1, AC-2 groups than control group. Conclusions : These results suggest that acupuncture at SP3·HT7 and SP3·HT7·LR1·KI1 can be used as a therapy for controlling renal hypertension induced by 2K1C in the rats.
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目次
ABSTRACT = ⅰ
Ⅰ. 緖論 = 1
Ⅱ. 材料 및 方法 = 3
1. 재료 = 3
1) 동물 = 3
2. 방법 = 3
1) 2 Kidney, 1 Clip(2K1C) 高血壓 유발 = 3
2) 取穴 = 4
3) 군 분리 = 4
4) 鍼刺 施術 = 4
5) 혈압 측정 = 5
6) 심장비대지수 측정 = 5
7) 혈장 ANP 측정 = 5
8) 혈장 Renin 측정 = 6
3. 통계처리 = 7
Ⅲ. 成績 = 8
1. 혈압 변화에 미치는 효과 = 8
2. 심장비대지수에 미치는 효과 = 10
3. 혈장 Renin에 미치는 효과 = 11
4. 혈장 ANP에 미치는 효과 = 12
Ⅳ. 考察 = 13
Ⅴ. 結論 = 18
參考文獻 = 19