六君子湯이 肥滿마우스의 體重및 血淸含量變化에 미치는 影響
(The) Effects of Yukgunja-Tang on the change of weight and serum level in mice fed high fat diet
초록/요약
This experimental study was designed to investigate the effects of Yukgunja-Tang(YGJT) on the change of weight and serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid and phospholipid level in obese mice induced by high fat diet. Experimental groups were as follows ; normal group was fed normal diet and administered DDW 0.2 ㎖ during 7 weeks, control group was fed high fat diet and administered DDW 0.2 ㎖ during 7 weeks, sample A group was fed high fat diet and administered YGJT 300 ㎎/㎏ 0.2 ㎖ during 7 weeks, sample B group was fed high fat diet and administered YGJT 500 ㎎/㎏ 0.2 ㎖ during 7 weeks. The results were as follows ; 1. Sample A group and Sample B group were significantly decreased body weight(4weeks) and serum free fatty acid level in comparison with control group. 2. Sample A group was significantly decreased body weight(7weeks), serum total cholesterol level and serum total lipid level but significantly increased serum HDL-cholesterol level in comparison with control group. 3. Sample A group was decreased serum LDL-cholesterol level, serum triglyceride level and serum phospholipid level in comparison with control group. 4. Sample B group was increased serum HDL-cholesterol level in comparison with control group. 5. Sample B group was decreased body weight(7weeks), serum total cholesterol level, serum LDL-cholesterol level, serum triglyceride level, serum total lipid level and serum phospholipid level in comparison with control group. According to above results, I suggest YGJT is able to be used for the obesity.
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目次
ABSTRACT = i
Ⅰ. 緖論 = 1
Ⅱ. 材料 및 方法 = 3
1. 재료 = 3
1) 동물 = 3
2) 약재 = 3
2. 방법 = 3
1) 검액의 조제 = 3
2) 비만유도 및 실험군 분류 = 4
3) 체중측정 = 4
4) 채혈 및 혈청분리 = 5
5) 혈청 지질함량 측정 = 5
3. 통계처리 = 6
Ⅲ. 實驗成績 = 7
1. 체중변화에 미치는 영향 = 7
2. 혈청중 Total cholesterol 함량에 미치는 영향 = 9
3. 혈청중 HDL-cholesterol 함량에 미치는 영향 = 11
4. 혈청중 LDL-cholesterol 함량에 미치는 영향 = 12
5. 혈청중 Triglyceride 함량에 미치는 영향 = 13
6. 혈청 중 Free fatty acid 함량에 미치는 영향 = 14
7. 혈청중 Total lipid 함량에 미치는 영향 = 15
8. 혈청중 Phospholipid 함량에 미치는 영향 = 16
Ⅳ. 考察 = 17
Ⅴ. 結論 = 21
參考文獻 = 22