二陳湯加蒼朮白朮이 고지방 식이로 유발된 생쥐의 비만증에 미치는 영향
An Experimental Effects of Ijintang add Atractylodis rhizoma and Atratcylodis macrocephalae rhizoma Extract in Obese Mice Induced by High Fat Diet
- 주제(키워드) 시료의 조제 , 비만 유도 및 실험군 분류 , 체중측정
- 발행기관 동신대학교 대학원
- 지도교수 정현우
- 발행년도 2008
- 학위수여년월 2008. 2
- 학위명 석사
- 학과 대학원 한의학과
- 원문페이지 ii, 23 p.
- 본문언어 한국어
초록/요약
This experimental study was designed to investigate the effects of Ijintang add Atractylodis rhizoma and Atratcylodis macrocephalae rhizoma (IJTAA) on the change of weight and serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid and phospholipid level in obese mice induced by high fat diet. Experimental groups were as follows ; Normal group was fed normal diet and administered distilled water during 7 weeks, Control group was fed high fat diet and administered distilled water during 7 weeks, Sample A group was fed high fat diet and administered IJTAA 500 ㎎/㎏/day/mouse during 7 weeks, Sample B group was fed high fat diet and administered IJTAA 700 ㎎/㎏/day/mouse during 7 weeks. The results were as follows ; 1. In Sample A group and Sample B group, There were significantly decreased in body weight, serum total cholesterol level, serum triglyceride level, serum free fatty acid level, serum total lipid level and serum phospholipid level in comparison with Control group. 2. In Sample A group and Sample B group, There were significantly increased in serum HDL-cholesterol level in comparison with Control group. 3. In Sample A group and Sample B group, There were decreased in serum LDL-cholesterol level in comparison with Control group. According to above results, I suggest IJTAA is able to be used for managing obesity by controllong body weight, serum total cholesterol level, serum triglyceride level, serum free fatty acid level, serum total lipid level and serum phospholipid level.
more목차
Ⅰ. 서론 = 1
Ⅱ. 재료 및 방법 = 3
1. 재료 = 3
1) 동물 = 3
2) 약재 = 3
2. 방법 = 4
1) 시료의 조제 = 4
2) 비만 유도 및 실험군 분류 = 4
3) 체중측정 = 5
3) 채혈 및 혈청 중 지질 함량 측정 = 5
3. 통계처리 = 6
Ⅲ. 실험성적 = 7
1. 체중에 미치는 효과 = 7
2. 혈청 중 total cholesterol, HDL-cholesterol, LDL-cholesterol 함량에 미치는 효과 = 9
3. 혈청 중 triglyceride, free fatty acid 함량에 미치는 효과 = 11
4. 혈청 중 total lipid, phospholipid 함량에 미치는 효과 = 13
Ⅳ. 고찰 = 15
Ⅴ. 결론 = 19
참고문헌 = 20