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蓮根이 Streptozotocin으로 유발된 糖尿病 白鼠의 血糖 및 血中 脂質에 미치는 影響

Effects of Nelumbinis Rhizomatis Nodus on Blood Glucose and Serum Lipid Levels in Streptozotocin-Induced Diabetic Rats

초록/요약

Objectives: The study was designed to investigate the effects of Nelumbinis Rhizomatis Nodus(NRN) on production levels of total cholesterol, triglyceride, BUN and creatine in serum. Methods: After treatment with NRN, blood glucose levels, body weights, food and water uptake, total cholesterol, triglyceride, creatinine, BUN of diabetic rats were measured. Results: Treatment with NRN regulated blood glucose levels effectively. But treatment with NRN did not affect body weights, food and water uptake. In addition, treatment with NRN also lowered levels of total cholesterol, which elevated by induction of Diabetes, and also lowered levels of triglyceride, too. Serum creatinine levels were not affected but, serum BUN levels were lowered by treatment with NRN, which were elevated by induction of Diabetes. Conclusions: These results demonstrate that NRN is effective to treat DM level and also has anti-hyperlipidemic effect.

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목차

Ⅰ. 緖論 = 1
Ⅱ. 材料 및 方法 = 3
1. 재료 = 3
1) 동물 = 3
2) 약재 = 3
3) 시약 및 기기 = 3
2. 방법 = 4
1) 시료의 조제 = 4
2) 당뇨병의 유발 = 4
3) 실험군의 선정 = 5
4) 공복 시 혈당 및 체중의 측정 = 6
5) 식이량 및 음수량 측정 = 6
6) 혈중 지질 및 BUN, Creatinine 함량 측정 = 7
3. 통계 처리 = 7
Ⅲ. 實驗成績 = 8
1. 공복 시 혈당변화에 미치는 영향 = 8
2. 체중 변화에 미치는 영향 = 10
3. 식이량 및 음수량 변동에 미치는 영향 = 12
4. 혈중 Total cholesterol 함량에 미치는 영향 = 14
5. 혈중 HDL cholesterol 함량에 미치는 영향 = 16
6. 혈중 Tryglyceride 함량에 미치는 영향 = 18
7. 혈중 BUN 함량에 미치는 영향 = 20
8. 혈중 Creatinine 함량에 미치는 영향 = 22
Ⅳ. 考察 = 24
Ⅴ. 結論 = 31
參考文獻 = 32

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