中脘(CV12) 황기약침이 노화촉진생쥐의 골다공증 개선에 미치는 영향
- 주제(키워드) 황기약침
- 발행기관 동신대학교 대학원
- 지도교수 김재홍
- 발행년도 2011
- 학위수여년월 2011. 2
- 학위명 석사
- 학과 및 전공 대학원 한의학과
- 실제URI http://www.dcollection.net/handler/dsu/000000889207
- 본문언어 한국어
- 저작권 동신대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Objective : The purpose of this study was to examine the effects of the Astragali radix Pharmacupuncture on improvement of senile osteoporosis (Type 2) in SAM P6. Methods : At 10 weeks after birth, Astragali radix Pharmacupunctures were given 100mL, 200mL/kg/day, i.p. 3times a week for 4 weeks at CV12 in SAM P6 mice. We measured complete blood cells (CBC) such as RBC, HGB, Hct, PLT, MPB and MCHC. And we analyzed the plasma concentrations of blood urea nitrogen, creatinine, inorganic phosphate and total iron. In addition, we tested bone mineral density (BMD) using the soft X-ray. Result : The results were as follows. 1. At CV12 in SAM P6, treatments of Astragali radix Pharmacupuncture were showed a trend of increase in bone mineral density (BMD) of the vertebrae lumbales, femurand tibia in P6 mice. 2. At CV12 in SAM P6, treatment of Astragali radix Pharmacupuncture increased in RBC, HB, HCT and PLT, in comparison with control group. It was also found that the inorganic phosphate levels increased in the treatment on groups of the Astragali radix Pharmacupuncture from that of the control group, but blood urea nitrogen was no significant. Conclusion : These results are suggested that at CV12 the Astragali radix Pharmacupuncture help on improvement of osteoporosis in SAMs.
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ABSTRACT 1
Ⅰ.緖論 3
Ⅱ.材料 및 方法 5
1. 실험재료 5
1) 실험동물 5
2) 약침의 제조 5
2. 실험방법 6
1) 골다공증 모델 선정 6
2) 실험동물군의 분류 7
3) 취혈 7
4) 투여 7
3. 결과 측정 8
1) 체중 측정 8
2) 골밀도 측정 8
3) 혈구 분석 실험 8
4) 혈액 생화학적 검사 9
4. 통계처리 9
Ⅲ.結果 10
1. 체중 10
2. 골밀도 측정 12
3. 혈구 분석 실험 17
4. 혈액 생화학적 검사 20
Ⅳ.考察 23
Ⅴ.結論 29
Ⅵ.參考文獻 30